The genetic advantage hypothesis in cystic fibrosis heterozygotes: a murine study.

1. The delta F508 mutation of the cystic fibrosis (CF) gene is of high frequency in man (1 in 25) and in homozygotes causes cystic fibrosis. It is suggested that cystic fibrosis heterozygotes withstand secretory diarrhoea better than normal individuals and so are genetically advantaged. This hypothe...

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Bibliografske podrobnosti
Main Authors: Cuthbert, A W, Halstead, J, Ratcliff, R, Colledge, W H, Evans, M J
Format: Artigo
Jezik:Inglês
Izdano: 1995
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1157742/
https://ncbi.nlm.nih.gov/pubmed/7714835
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