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Mechanisms of quinolone resistance in Escherichia coli: characterization of nfxB and cfxB, two mutant resistance loci decreasing norfloxacin accumulation.

Two genetic loci selected for norfloxacin (nfxB) and ciprofloxacin (cfxB) resistance were characterized. Both mutations have previously been shown to confer pleiotropic resistance to quinolones, chloramphenicol, and tetracycline and to decrease expression of porin outer-membrane protein OmpF. nfxB w...

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Publicado en:Antimicrob Agents Chemother
Autores principales: Hooper, D C, Wolfson, J S, Souza, K S, Ng, E Y, McHugh, G L, Swartz, M N
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1989
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC171480/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2658782/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.33.3.283
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