In vitro and in vivo uptake of azithromycin (CP-62,993) by phagocytic cells: possible mechanism of delivery and release at sites of infection.

Azithromycin, a novel azalide antibiotic, concentrated in human and mouse polymorphonuclear leukocytes (PMNs), murine peritoneal macrophages, and mouse and rat alveolar macrophages, attaining intracellular concentrations up to 226 times the external concentration in vitro. In murine peritoneal macro...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Gladue, R P, Bright, G M, Isaacson, R E, Newborg, M F
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1989
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC171479/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2543276/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.33.3.277
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