In vitro and in vivo uptake of azithromycin (CP-62,993) by phagocytic cells: possible mechanism of delivery and release at sites of infection.

Azithromycin, a novel azalide antibiotic, concentrated in human and mouse polymorphonuclear leukocytes (PMNs), murine peritoneal macrophages, and mouse and rat alveolar macrophages, attaining intracellular concentrations up to 226 times the external concentration in vitro. In murine peritoneal macro...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Gladue, R P, Bright, G M, Isaacson, R E, Newborg, M F
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1989
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC171479/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2543276/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.33.3.277
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