In vitro and in vivo uptake of azithromycin (CP-62,993) by phagocytic cells: possible mechanism of delivery and release at sites of infection.

Azithromycin, a novel azalide antibiotic, concentrated in human and mouse polymorphonuclear leukocytes (PMNs), murine peritoneal macrophages, and mouse and rat alveolar macrophages, attaining intracellular concentrations up to 226 times the external concentration in vitro. In murine peritoneal macro...

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Detalles Bibliográficos

Publicado en:	Antimicrob Agents Chemother
Autores principales:	Gladue, R P, Bright, G M, Isaacson, R E, Newborg, M F
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 1989
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC171479/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2543276/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.33.3.277
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