Efficacy of phosphonylmethoxyalkyl derivatives of adenine in experimental herpes simplex virus and vaccinia virus infections in vivo.

The phosphonylmethoxyalkyl derivatives (S)-9-(3-hydroxy-2-phosphonylmethoxypropyl)adenine [(S)-HPMPA], 9-(2-phosphonylmethoxyethyl)adenine (PMEA), and 9-(2-phosphonylmethoxyethyl)-2,6-diaminopurine (PMEDAP) were evaluated for their in vivo efficacies in several animal model infections, i.e., mice in...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	De Clercq, E, Holý, A, Rosenberg, I
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1989
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC171454/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2719463/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.33.2.185
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