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Efficacy of phosphonylmethoxyalkyl derivatives of adenine in experimental herpes simplex virus and vaccinia virus infections in vivo.

The phosphonylmethoxyalkyl derivatives (S)-9-(3-hydroxy-2-phosphonylmethoxypropyl)adenine [(S)-HPMPA], 9-(2-phosphonylmethoxyethyl)adenine (PMEA), and 9-(2-phosphonylmethoxyethyl)-2,6-diaminopurine (PMEDAP) were evaluated for their in vivo efficacies in several animal model infections, i.e., mice in...

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Main Authors: De Clercq, E, Holý, A, Rosenberg, I
Format: Artigo
Jezik:Inglês
Izdano: 1989
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC171454/
https://ncbi.nlm.nih.gov/pubmed/2719463
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