The potential for gene repair via triple helix formation
Triplex-forming oligonucleotides (TFOs) can bind to polypurine/polypyrimidine regions in DNA in a sequence-specific manner. The specificity of this binding raises the possibility of using triplex formation for directed genome modification, with the ultimate goal of repairing genetic defects in human...
שמור ב:
| הוצא לאור ב: | J Clin Invest |
|---|---|
| Principais autores: | , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Society for Clinical Investigation
2003
|
| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC171401/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12925687/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI19552 |
| תגים: |
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!
|