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Decrypting the role of Cripto in tumorigenesis

The cell-surface associated molecule Cripto is overexpressed in a wide range of epithelial cancers, yet little is known about potential mechanisms by which Cripto expression might enhance tumorigenesis. A new study reveals that binding of Cripto to the TGF-β ligand Activin B can block Activin B–medi...

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Bibliographic Details
Main Author: Shen, Michael M.
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2003
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC171399/
https://ncbi.nlm.nih.gov/pubmed/12925690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200319546
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