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Decrypting the role of Cripto in tumorigenesis

The cell-surface associated molecule Cripto is overexpressed in a wide range of epithelial cancers, yet little is known about potential mechanisms by which Cripto expression might enhance tumorigenesis. A new study reveals that binding of Cripto to the TGF-β ligand Activin B can block Activin B–medi...

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Pubblicato in:J Clin Invest
Autore principale: Shen, Michael M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2003
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC171399/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12925690/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI19546
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