Загрузка...

Dysregulated Sonic hedgehog signaling and medulloblastoma consequent to IFN-α–stimulated STAT2-independent production of IFN-γ in the brain

The type I IFNs (IFN-α and IFN-β), which are crucial in antiviral defense and immune regulation, signal via the Janus kinase/signal transducer and activator of transcription (JAK/STAT) pathway with activation of STAT1 and STAT2. Here, the function of STAT2 was studied in transgenic mice (termed GIFN...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Wang, Jianping, Pham-Mitchell, Ngan, Schindler, Christian, Campbell, Iain L.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 2003
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC171394/
https://ncbi.nlm.nih.gov/pubmed/12925694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200318637
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!