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Cathepsin V is involved in the degradation of invariant chain in human thymus and is overexpressed in myasthenia gravis

Stepwise degradation of the invariant chain (Ii) is required for the binding of antigenic peptides to MHC class II molecules. Cathepsin (Cat) L in the murine thymus and Cat S in peripheral APCs have both been implicated in the last step of Ii degradation that gives rise to the class II–associated in...

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Detalhes bibliográficos
Main Authors: Tolosa, Eva, Li, Weijie, Yasuda, Yoshiyuki, Wienhold, Wolfgang, Denzin, Lisa K., Lautwein, Alfred, Driessen, Christoph, Schnorrer, Petra, Weber, Ekkehard, Stevanovic, Stefan, Kurek, Raffael, Melms, Arthur, Brömme, Dieter
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC171390/
https://ncbi.nlm.nih.gov/pubmed/12925692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200318028
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