Method for induction of mutations in physically defined regions of the herpes simplex virus genome.

A procedure was developed for inducing mutations in isolated restriction enzyme fragments of herpes simplex virus type 1 (HSV-1) DNA with nitrous acid. The mutations were then transferred to the viral genome by genetic recombination during cotransfection of rabbit kidney cells with the mutagenized f...

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Bibliografiske detaljer

Udgivet i:	J Virol
Principais autores:	Sandri-Goldin, R M, Levine, M, Glorioso, J C
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1981
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC171124/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6264113/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.38.1.41-49.1981
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