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Prediction of clinical drug efficacy by classification of drug-induced genomic expression profiles in vitro
Assays of drug action typically evaluate biochemical activity. However, accurately matching therapeutic efficacy with biochemical activity is a challenge. High-content cellular assays seek to bridge this gap by capturing broad information about the cellular physiology of drug action. Here, we presen...
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Autores principales: | , , , , |
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Formato: | Artigo |
Lenguaje: | Inglês |
Publicado: |
National Academy of Sciences
2003
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Materias: | |
Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC170965/ https://ncbi.nlm.nih.gov/pubmed/12869696 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1632587100 |
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