Differential regulation of microtubule dynamics by three- and four-repeat tau: Implications for the onset of neurodegenerative disease

The microtubule (MT)-associated protein tau is important in neuronal development and in Alzheimer's and other neurodegenerative diseases. Genetic analyses have established a cause-and-effect relationship between tau dysfunction/misregulation and neuronal cell death and dementia in frontotemporal dem...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Panda, Dulal, Samuel, Jonathan C., Massie, Michelle, Feinstein, Stuart C., Wilson, Leslie
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 2003
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC170955/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12886013/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1633508100
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