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Insig-1 “brakes” lipogenesis in adipocytes and inhibits differentiation of preadipocytes
We have examined gene expression in the fat tissue of normal mice at the onset of diet-induced obesity. Insulin-induced gene 1 (insig-1) mRNA rose progressively with a high-fat diet and declined on a restricted diet. Because insig-1 binds sterol regulatory element-binding protein cleavage-activating...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC170943/ https://ncbi.nlm.nih.gov/pubmed/12869692 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1133426100 |
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