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Stimulation of T cell autoreactivity by anomalous expression of NKG2D and its MIC ligands in rheumatoid arthritis

Effector T cell responses can be modulated by competing positive or negative signals transduced by natural killer (NK) cell receptors. This raises the possibility that dominant T cell stimulation might promote autoimmune reactions. In rheumatoid arthritis (RA), the severity of autoimmune and inflamm...

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Detalhes bibliográficos
Main Authors: Groh, Veronika, Brühl, Anja, El-Gabalawy, Hani, Nelson, J. Lee, Spies, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC170939/
https://ncbi.nlm.nih.gov/pubmed/12878725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1632807100
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