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The lipoxygenase gene ALOXE3 implicated in skin differentiation encodes a hydroperoxide isomerase
Lipoxygenase (LOX) enzymes form fatty acid hydroperoxides used in membrane remodeling and cell signaling. Mammalian epidermal LOX type 3 (eLOX3) is distinctive in totally lacking this typical oxygenase activity. Surprisingly, genetic evidence has linked mutations in eLOX3 or a colocalizing enzyme, 1...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2003
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC170889/ https://ncbi.nlm.nih.gov/pubmed/12881489 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1633612100 |
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