The lipoxygenase gene ALOXE3 implicated in skin differentiation encodes a hydroperoxide isomerase

Lipoxygenase (LOX) enzymes form fatty acid hydroperoxides used in membrane remodeling and cell signaling. Mammalian epidermal LOX type 3 (eLOX3) is distinctive in totally lacking this typical oxygenase activity. Surprisingly, genetic evidence has linked mutations in eLOX3 or a colocalizing enzyme, 1...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Yu, Zheyong, Schneider, Claus, Boeglin, William E., Marnett, Lawrence J., Brash, Alan R.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 2003
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC170889/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12881489/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1633612100
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