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Depletion of endogenous interleukin-10 augments interleukin-1 beta secretion by Mycobacterium bovis BCG-reactive human cells.

In this study, we found evidence that the interleukin-10 (IL-10) protein is functionally relevant in Mycobacterium bovis BCG-induced cytokine synthesis, as neutralization of endogenously synthesized IL-10 in human cells activated with BCG resulted in a two- to threefold increase in the level of IL-1...

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Bibliographic Details
Published in:Clin Diagn Lab Immunol
Main Authors: Méndez-Samperio, P, Garcia-Martinez, E, Hernandez-Garay, M, Solis-Cardona, M
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1997
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Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC170492/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9067646/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/cdli.4.2.138-141.1997
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