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Anti-emetic activity of phenothiazines in relation to their chemical structure
Twelve phenothiazine derivatives have been studied for anti-emetic potency in dogs against emesis induced by apomorphine. The PD(50)s of all the compounds were determined and the activities compared with chlorpromazine hydrochloride as standard. Thioproperazine methanesulphonate was 300 times more a...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1963
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1703878/ https://ncbi.nlm.nih.gov/pubmed/14110743 |
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