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Development of mucosal and systemic lymphoproliferative responses and protective immunity to human group A rotaviruses in a gnotobiotic pig model.

Gnotobiotic pigs were orally inoculated with virulent Wa strain (G1P1A[8]) human rotavirus (group 1), attenuated Wa rotavirus (group 2) or diluent (controls) and were challenged with virulent Wa rotavirus 21 days later. On various postinoculation or postchallenge days, virus-specific responses of sy...

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Bibliographic Details
Main Authors: Ward, L A, Yuan, L, Rosen, B I, Tô, T L, Saif, L J
Format: Artigo
Language:Inglês
Published: 1996
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC170344/
https://ncbi.nlm.nih.gov/pubmed/8705681
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