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Combination of DNA-directed immobilization and immuno-PCR: very sensitive antigen detection by means of self-assembled DNA–protein conjugates

An assay for very sensitive antigen detection is described which takes advantage of the self- assembly capabilities of semi-synthetic conjugates of DNA and proteins. The general scheme of this assay is similar to a two-sided (sandwich) enzyme-linked immunoassay (ELISA); however, covalent single-stra...

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Bibliografiske detaljer
Main Authors: Niemeyer, Christof M., Wacker, Ron, Adler, Michael
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC169982/
https://ncbi.nlm.nih.gov/pubmed/12907742
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