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Controlling nucleic acid secondary structure by intercalation: effects of DNA strand length on coralyne-driven duplex disproportionation

Small molecules that intercalate in DNA and RNA are powerful agents for controlling nucleic acid structural transitions. We recently demonstrated that coralyne, a small crescent-shaped molecule, can cause the complete and irreversible disproportionation of duplex poly(dA)·poly(dT) into triplex poly(...

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Détails bibliographiques
Auteurs principaux: Jain, Swapan S., Polak, Matjaž, Hud, Nicholas V.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2003
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC169941/
https://ncbi.nlm.nih.gov/pubmed/12888521
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