c-myc as a mediator of accelerated apoptosis and involution in mammary glands lacking Socs3

Suppressor of cytokine signalling (SOCS) proteins are critical attenuators of cytokine-mediated signalling in diverse tissues. To determine the importance of Socs3 in mammary development, we generated mice in which Socs3 was deleted in mammary epithelial cells. No overt phenotype was evident during...

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Hauptverfasser: Sutherland, Kate D, Vaillant, François, Alexander, Warren S, Wintermantel, Tim M, Forrest, Natasha C, Holroyd, Sheridan L, McManus, Edward J, Schutz, Gunther, Watson, Christine J, Chodosh, Lewis A, Lindeman, Geoffrey J, Visvader, Jane E
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2006
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698901/
https://ncbi.nlm.nih.gov/pubmed/17139252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601455
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