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Sequence–structure–function relationships of Tgs1, the yeast snRNA/snoRNA cap hypermethylase

The Saccharomyces cerevisiae Tgs1 methyltransferase (MTase) is responsible for conversion of the m(7)G caps of snRNAs and snoRNAs to a 2,2,7- trimethylguanosine structure. To learn more about the evolutionary origin of Tgs1 and to identify structural features required for its activity, we performed...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Principais autores: Mouaikel, John, Bujnicki, Janusz M., Tazi, Jamal, Bordonné, Rémy
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2003
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC169889/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12907733/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkg656
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