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AKAP150, a switch to convert mechano-, pH- and arachidonic acid-sensitive TREK K(+) channels into open leak channels

TREK channels are unique among two-pore-domain K(+) channels. They are activated by polyunsaturated fatty acids (PUFAs) including arachidonic acid (AA), phospholipids, mechanical stretch and intracellular acidification. They are inhibited by neurotransmitters and hormones. TREK-1 knockout mice have...

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מידע ביבליוגרפי
Main Authors: Sandoz, Guillaume, Thümmler, Susanne, Duprat, Fabrice, Feliciangeli, Sylvain, Vinh, Joëlle, Escoubas, Pierre, Guy, Nicolas, Lazdunski, Michel, Lesage, Florian
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group 2006
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698884/
https://ncbi.nlm.nih.gov/pubmed/17110924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601437
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