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p53 mediates the negative regulation of MDM2 by orphan receptor TR3
MDM2 is an oncoprotein whose transforming potential is activated by overexpression. The expression level of MDM2 is negatively regulated by orphan receptor TR3 that mainly acts as a transcriptional factor to regulate gene expression. However, the underlying mechanism is largely unclear. Here, we pre...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2006
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1698882/ https://ncbi.nlm.nih.gov/pubmed/17139261 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601435 |
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