Activated Human T Lymphocytes Express Cyclooxygenase-2 and Produce Proadipogenic Prostaglandins that Drive Human Orbital Fibroblast Differentiation to Adipocytes

The differentiation of preadipocyte fibroblasts to adipocytes is a crucial process to many disease states including obesity, cardiovascular, and autoimmune diseases. In Graves’ disease, the orbit of the eye can become severely inflamed and infiltrated with T lymphocytes as part of the autoimmune pro...

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Autores principales: Feldon, Steven E., O’Loughlin, Charles W., Ray, Denise M., Landskroner-Eiger, Shira, Seweryniak, Kathryn E., Phipps, Richard P.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Investigative Pathology 2006
Materias:
Regular Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698858/
https://ncbi.nlm.nih.gov/pubmed/17003477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.060434
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