Oligodendrocytes Are a Major Target of the Toxicity of Spongiogenic Murine Retroviruses

The neurovirulent retroviruses FrCasE and Moloney MLV-ts1 cause noninflammatory spongiform neurodegeneration in mice, manifested clinically by progressive spasticity and paralysis. Neurons have been thought to be the primary target of toxicity of these viruses. However the neurons themselves appear...

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Main Authors: Clase, Amanda C., Dimcheff, Derek E., Favara, Cynthia, Dorward, David, McAtee, Frank J., Parrie, Lindsay E., Ron, David, Portis, John L.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2006
Teme:
Regular Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698807/
https://ncbi.nlm.nih.gov/pubmed/16936275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.051357
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