p62 Ubiquitin Binding-Associated Domain Mediated the Receptor Activator of Nuclear Factor-κB Ligand-Induced Osteoclast Formation : A New Insight into the Pathogenesis of Paget’s Disease of Bone

Paget’s disease of bone (PDB) is a debilitating bone disorder characterized by giant osteoclasts, enhanced bone destruction, and irregular bone formation. Recently, mutations in SQSTM1 (also known as p62) have been detected in PDB sufferers, with all mutations resulting in either loss of function or...

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Detalhes bibliográficos
Main Authors: Yip, Kirk H.M., Feng, Haotian, Pavlos, Nathan J., Zheng, Ming H., Xu, Jiake
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2006
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698794/
https://ncbi.nlm.nih.gov/pubmed/16877352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.050960
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