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HBx-dependent cell cycle deregulation involves interaction with cyclin E/A–cdk2 complex and destabilization of p27(Kip1)

The HBx (X protein of hepatitis B virus) is a promiscuous transactivator implicated to play a key role in hepatocellular carcinoma. However, HBx-regulated molecular events leading to deregulation of cell cycle or establishment of a permissive environment for hepatocarcinogenesis are not fully unders...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Mukherji, Atish, Janbandhu, Vaibhao C., Kumar, Vijay
Format: Artigo
Sprache:Inglês
Veröffentlicht: Portland Press Ltd. 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698683/
https://ncbi.nlm.nih.gov/pubmed/16939421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20061091
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