Rapid Simultaneous Detection by Real-Time PCR of Cytomegalovirus UL97 Mutations in Codons 460 and 520 Conferring Ganciclovir Resistance

Ganciclovir (GCV) resistance is an emerging problem for transplant recipients. A sensitive and rapid real-time PCR approach for simultaneous and semiquantitative detection of human cytomegalovirus (HCMV) UL97 mutations in codons 460/520 was established by LightCycler and confirmed by restriction fra...

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Bibliographic Details
Main Authors: Göhring, Katharina, Mikeler, Elfriede, Jahn, Gerhard, Hamprecht, Klaus
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2006
Subjects:
Virology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698385/
https://ncbi.nlm.nih.gov/pubmed/17035493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.01141-06
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