Identification of a Gene Negatively Affecting Antibiotic Production and Morphological Differentiation in Streptomyces coelicolor A3(2)

SC7A1 is a cosmid with an insert of chromosomal DNA from Streptomyces coelicolor A3(2). Its insertion into the chromosome of S. coelicolor strains caused a duplication of a segment of ca. 40 kb and delayed actinorhodin antibiotic production and sporulation, implying that SC7A1 carried a gene negativ...

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Bibliographische Detailangaben
Hauptverfasser: Li, Wencheng, Ying, Xin, Guo, Yuzheng, Yu, Zhen, Zhou, Xiufen, Deng, Zixin, Kieser, Helen, Chater, Keith F., Tao, Meifeng
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2006
Schlagworte:
Physiology and Metabolism
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698255/
https://ncbi.nlm.nih.gov/pubmed/17041057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00933-06
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