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Characterization of 2-Bromoethanesulfonate as a Selective Inhibitor of the Coenzyme M-Dependent Pathway and Enzymes of Bacterial Aliphatic Epoxide Metabolism

Bacterial growth with short-chain aliphatic alkenes requires coenzyme M (CoM) (2-mercaptoethanesulfonic acid), which serves as the nucleophile for activation and conversion of epoxide products formed from alkene oxidation to central metabolites. In the present work the CoM analog 2-bromoethanesulfon...

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Hlavní autoři: Boyd, Jeffrey M., Ellsworth, Ashley, Ensign, Scott A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698180/
https://ncbi.nlm.nih.gov/pubmed/16997966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00947-06
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