Up-Regulation of Gamma Interferon Receptor Expression Due to Chlamydia-Toll-Like Receptor Interaction Does Not Enhance Signal Transducer and Activator of Transcription 1 Signaling

Gamma interferon (IFN-γ)-induced indoleamine dioxygenase (IDO), which inhibits chlamydial replication by reducing the availability of tryptophan, is up-regulated by interleukin-1β (IL-1β) and tumor necrosis factor alpha (TNF-α). The mechanisms by which this occurs include an increase in the synthesi...

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Bibliographic Details
Main Authors: Shirey, Kari Ann, Jung, Joo-Yong, Carlin, Joseph M.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2006
Subjects:
Host Response and Inflammation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698061/
https://ncbi.nlm.nih.gov/pubmed/17030574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00505-06
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