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pK(a) Values for Side-Chain Carboxyl Groups of a PGB1 Variant Explain Salt and pH-Dependent Stability

Determination of pK(a) values of titrating residues in proteins provides a direct means of studying electrostatic coupling as well as pH-dependent stability. The B1 domain of protein G provides an excellent model system for such investigations. In this work, we analyze the observed pK(a) values of a...

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Detalhes bibliográficos
Main Authors: Lindman, Stina, Linse, Sara, Mulder, Frans A. A., André, Ingemar
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1697841/
https://ncbi.nlm.nih.gov/pubmed/17040982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.088682
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