Expressed in the Yeast Saccharomyces cerevisiae, Human ERK5 Is a Client of the Hsp90 Chaperone That Complements Loss of the Slt2p (Mpk1p) Cell Integrity Stress-Activated Protein Kinase

ERK5 is a mitogen-activated protein (MAP) kinase regulated in human cells by diverse mitogens and stresses but also suspected of mediating the effects of a number of oncogenes. Its expression in the slt2Δ Saccharomyces cerevisiae mutant rescued several of the phenotypes caused by the lack of Slt2p (...

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Main Authors: Truman, Andrew W., Millson, Stefan H., Nuttall, James M., King, Victoria, Mollapour, Mehdi, Prodromou, Chrisostomos, Pearl, Laurence H., Piper, Peter W.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2006
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1694803/
https://ncbi.nlm.nih.gov/pubmed/16950928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00263-06
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