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Position-dependent effects of locked nucleic acid (LNA) on DNA sequencing and PCR primers

Genomes are becoming heavily annotated with important features. Analysis of these features often employs oligonucleotides that hybridize at defined locations. When the defined location lies in a poor sequence context, traditional design strategies may fail. Locked Nucleic Acid (LNA) can enhance olig...

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Bibliografski detalji
Glavni autori: Levin, Joshua D., Fiala, Dean, Samala, Meinrado F., Kahn, Jason D., Peterson, Raymond J.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2006
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1694044/
https://ncbi.nlm.nih.gov/pubmed/17071964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl756
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