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Position-dependent effects of locked nucleic acid (LNA) on DNA sequencing and PCR primers

Genomes are becoming heavily annotated with important features. Analysis of these features often employs oligonucleotides that hybridize at defined locations. When the defined location lies in a poor sequence context, traditional design strategies may fail. Locked Nucleic Acid (LNA) can enhance olig...

詳細記述

保存先:
書誌詳細
主要な著者: Levin, Joshua D., Fiala, Dean, Samala, Meinrado F., Kahn, Jason D., Peterson, Raymond J.
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2006
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1694044/
https://ncbi.nlm.nih.gov/pubmed/17071964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl756
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