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Glibenclamide, a Blocker of K(+)(ATP) Channels, Shows Antileishmanial Activity in Experimental Murine Cutaneous Leishmaniasis
Glibenclamide reduced the rate of lesion growth in BALB/c mice infected with Leishmania (Leishmania) mexicana, the effect was dose dependent, and the highest dose proved more effective than glucantime. Cross-resistance to glucantime was found in animals infected with a glibenclamide-resistant line,...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology
2006
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1693980/ https://ncbi.nlm.nih.gov/pubmed/17015627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00617-06 |
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