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Glibenclamide, a Blocker of K(+)(ATP) Channels, Shows Antileishmanial Activity in Experimental Murine Cutaneous Leishmaniasis

Glibenclamide reduced the rate of lesion growth in BALB/c mice infected with Leishmania (Leishmania) mexicana, the effect was dose dependent, and the highest dose proved more effective than glucantime. Cross-resistance to glucantime was found in animals infected with a glibenclamide-resistant line,...

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Hlavní autoři: Serrano-Martín, Xenón, Payares, Gilberto, Mendoza-León, Alexis
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1693980/
https://ncbi.nlm.nih.gov/pubmed/17015627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00617-06
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