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Transcription factor profiling in individual hematopoietic progenitors by digital RT-PCR

We report here a systematic, quantitative population analysis of transcription factor expression within developmental progenitors, made possible by a microfluidic chip-based “digital RT-PCR” assay that can count template molecules in cDNA samples prepared from single cells. In a survey encompassing...

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Bibliografiske detaljer
Main Authors: Warren, Luigi, Bryder, David, Weissman, Irving L., Quake, Stephen R.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1693828/
https://ncbi.nlm.nih.gov/pubmed/17098862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0608512103
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