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Recurrent duplication-driven transposition of DNA during hominoid evolution

The underlying mechanism by which the interspersed pattern of human segmental duplications has evolved is unknown. Based on a comparative analysis of primate genomes, we show that a particular segmental duplication (LCR16a) has been the source locus for the formation of the majority of intrachromoso...

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Detalhes bibliográficos
Main Authors: Johnson, Matthew E., Cheng, Ze, Morrison, V. Anne, Scherer, Steven, Ventura, Mario, Gibbs, Richard A., Green, Eric D., Eichler, Evan E.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1693797/
https://ncbi.nlm.nih.gov/pubmed/17101969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0605426103
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