Angiopoietin-like 4 prevents metastasis through inhibition of vascular permeability and tumor cell motility and invasiveness

Angiopoietin-like 4 (ANGPTL4), a secreted protein of the angiopoietin-like family, is induced by hypoxia in both tumor and endothelial cells as well as in hypoxic perinecrotic areas of numerous cancers. Here, we investigated whether ANGPTL4 might affect tumor growth as well as metastasis. Metastatic...

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Autors principals: Galaup, Ariane, Cazes, Aurelie, Le Jan, Sebastien, Philippe, Josette, Connault, Elisabeth, Le Coz, Emmanuelle, Mekid, Halima, Mir, Lluis M., Opolon, Paule, Corvol, Pierre, Monnot, Catherine, Germain, Stephane
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2006
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1693729/
https://ncbi.nlm.nih.gov/pubmed/17130448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609025103
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