Angiopoietin-like 4 prevents metastasis through inhibition of vascular permeability and tumor cell motility and invasiveness

Angiopoietin-like 4 (ANGPTL4), a secreted protein of the angiopoietin-like family, is induced by hypoxia in both tumor and endothelial cells as well as in hypoxic perinecrotic areas of numerous cancers. Here, we investigated whether ANGPTL4 might affect tumor growth as well as metastasis. Metastatic...

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Bibliographic Details
Main Authors: Galaup, Ariane, Cazes, Aurelie, Le Jan, Sebastien, Philippe, Josette, Connault, Elisabeth, Le Coz, Emmanuelle, Mekid, Halima, Mir, Lluis M., Opolon, Paule, Corvol, Pierre, Monnot, Catherine, Germain, Stephane
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2006
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1693729/
https://ncbi.nlm.nih.gov/pubmed/17130448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609025103
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