Reelin molecules assemble together to form a large protein complex, which is inhibited by the function-blocking CR-50 antibody

Reelin is a key mediator of ordered neuronal alignment in the brain. Here, we demonstrate that Reelin molecules assemble with each other to form a huge protein complex both in vitro and in vivo. The Reelin–Reelin interaction clearly is inhibited by the function-blocking anti-Reelin antibody, CR-50,...

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Main Authors: Utsunomiya-Tate, Naoko, Kubo, Ken-ichiro, Tate, Shin-ichi, Kainosho, Masatsune, Katayama, Eisaku, Nakajima, Kazunori, Mikoshiba, Katsuhiko
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 2000
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC16933/
https://ncbi.nlm.nih.gov/pubmed/10920200
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