Reelin molecules assemble together to form a large protein complex, which is inhibited by the function-blocking CR-50 antibody

Reelin is a key mediator of ordered neuronal alignment in the brain. Here, we demonstrate that Reelin molecules assemble with each other to form a huge protein complex both in vitro and in vivo. The Reelin–Reelin interaction clearly is inhibited by the function-blocking anti-Reelin antibody, CR-50,...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Utsunomiya-Tate, Naoko, Kubo, Ken-ichiro, Tate, Shin-ichi, Kainosho, Masatsune, Katayama, Eisaku, Nakajima, Kazunori, Mikoshiba, Katsuhiko
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2000
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC16933/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10920200/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.160272497
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