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Cadherins and synaptic plasticity: activity-dependent cyclin-dependent kinase 5 regulation of synaptic beta-catenin-cadherin interactions.

Cyclin-dependent kinase 5 (Cdk5)/p35 kinase activity is known to decrease the affinity of beta-catenin for cadherin in developing cortical neurons. Our recent work demonstrated that depolarization causes an increased affinity between beta-catenin and cadherin. Here, we examine whether Cdk5/p35 regul...

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Detalles Bibliográficos
Autores principales: Schuman, Erin M, Murase, Sachiko
Formato: Artigo
Lenguaje:Inglês
Publicado: 2003
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1693152/
https://ncbi.nlm.nih.gov/pubmed/12740122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2002.1256
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