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Cyclin-dependent kinase 5 governs learning and synaptic plasticity via control of NMDAR degradation
Learning is accompanied by modulation of postsynaptic signal transduction pathways in neurons. Although the neuronal protein kinase cyclin-dependent kinase 5 (Cdk5) has been implicated in cognitive disorders, its role in learning has been obscured by the perinatal lethality of constitutive knockout...
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| Glavni autori: | , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2007
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3910113/ https://ncbi.nlm.nih.gov/pubmed/17529984 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn1914 |
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