Blockade of the epidermal growth factor receptor tyrosine kinase suppresses tumorigenesis in MMTV/Neu + MMTV/TGF-α bigenic mice

Overexpression of ErbB-2/Neu has been causally associated with mammary epithelial transformation. Here we report that blockade of the epidermal growth factor receptor (EGFR) kinase with AG-1478 markedly delays breast tumor formation in mouse mammary tumor virus (MMTV)/Neu + MMTV/transforming growth...

全面介紹

書目詳細資料

發表在:	Proc Natl Acad Sci U S A
Principais autores:	Lenferink, Anne E. G., Simpson, Jean F., Shawver, Laura K., Coffey, Robert J., Forbes, James T., Arteaga, Carlos L.
格式:	Artigo
語言:	Inglês
出版:	National Academy of Sciences 2000
主題:	Biological Sciences
在線閱讀:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC16912/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10931950/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.160564197
標簽:	添加標簽 沒有標簽, 成為第一個標記此記錄!