Inhibition of IL-2-induced Jak-STAT signaling by glucocorticoids

Glucocorticoids (GCs) are potent anti-inflammatory agents that block cytokine production. We investigated whether GCs also block cytokine signaling via the Janus kinase (Jak)-signal transducer and activator of transcription (STAT) pathway. Dexamethasone inhibited IL-2-induced DNA binding, tyrosine p...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Bianchi, Marina, Meng, Charis, Ivashkiv, Lionel B.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 2000
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC16906/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10920190/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.160099797
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