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Phosphorylation-independent desensitization of GABA(B) receptor by GRK4

Agonist-promoted desensitization of the heterodimeric metabotropic GABA(B) receptor was investigated. Whereas no desensitization was observed in HEK293 cells heterologously expressing the receptor, GABA and the synthetic agonist baclofen induced a robust desensitization in cerebellar granule cells e...

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Hlavní autoři: Perroy, Julie, Adam, Lynda, Qanbar, Riad, Chénier, Sébastien, Bouvier, Michel
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC169056/
https://ncbi.nlm.nih.gov/pubmed/12881416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg383
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